Institute Director, National Institute of Molecular Biology and Biotechnology (2019 – 2021)
PhD, Pierre and Marie Curie University, Paris, France
MAS Public Health, Pierre and Marie Curie University, Paris, France
MS Molecular Biology and Biotechnology, University of the Philippines, DIliman, Philippines
BS Biology, University of the Philippines, Diliman, Philippines
The Molecular Toxicology Research Laboratory (TOX) was established in 2009. It develops tools to demonstrate cause-and-effect in drug studies, with the aim to improving safety and efficacy. The laboratory assesses genetic markers of effects following exposure to xenobiotics, evaluates genetic markers of risk and response, and develops methods for rapid, accurate, and economic assessment of risk and efficacy using genotyping, expression analysis, and bioassay.
Yuan Y, Li T, Wang T, Naman CB, Ye J, Wu X, Lazaro JEH, Yan X, He S. Targeted Isolation of a Cytotoxic Cyclic Hexadepsipeptide from the Mesophotic Zone Sponge-Associated Fungus Cymostachys sp. NBUF082. Mar Drugs. 2021 Oct 11;19(10):565. doi: 10.3390/md19100565. PMID: 34677465; PMCID: PMC8540034.
Zhou J, Zhang H, Ye J, Wu X, Wang W, Lin H, Yan X, Lazaro JEH, Wang T, Naman CB, He S. Cytotoxic Polyketide Metabolites from a Marine Mesophotic Zone Chalinidae Sponge-Associated Fungus Pleosporales sp. NBUF144. Mar Drugs. 2021 Mar 26;19(4):186. doi: 10.3390/md19040186. PMID: 33810590; PMCID: PMC8065988.
Wang T, Zhou J, Zou J, Shi Y, Zhou W, Shao P, Yu T, Cui W, Li X, Wu X, Ye J, Yan X, Naman CB, Lazaro JEH, He S. Discovery of Cymopolyphenols A-F From a Marine Mesophotic Zone Aaptos Sponge-Associated Fungus Cymostachys sp. NBUF082. Front Microbiol. 2021 Feb 22;12:638610. doi: 10.3389/fmicb.2021.638610. PMID: 33692772; PMCID: PMC7937805.
Ding L, Xu P, Zhang W, Yuan Y, He X, Su D, Shi Y, Naman CB, Yan X, Wu B, Lazaro JEH, Li S, He S. Three New Diketopiperazines from the Previously Uncultivable Marine Bacterium Gallaecimonas mangrovi HK-28 Cultivated by iChip. Chem Biodivers. 2020 Jul;17(7):e2000221. doi: 10.1002/cbdv.202000221. Epub 2020 Jun 23. PMID: 32347603.